Chiral monomers, bearing different quinidine derivatives, were copolymerize
d with achiral monomers, producing insoluble copolymers which were used for
the dihydroxylation of styrene as standard substrate. The structure of the
polymeric insoluble support was found to be of great importance in determi
ning the handling, efficiency, and enantioselectivity of the catalyst. The
comparison with a soluble model compound showed that the insoluble polymer-
bound ligand approach is very promising for both small- and large-scale syn
thesis of optically active vicinal diols. Chirality 11:745-751, 1999. (C) 1
999 Wiley-Liss, Inc.