Male prison inmates within 2 weeks of release were recruited to evaluate a
pre-release HIV prevention intervention. A total of 414 inmates were random
ly assigned to receive the intervention or to a comparison group. All parti
cipants completed a face-to-face survey at baseline; high rates of preincar
ceration at-risk behavior were reported. Follow-up telephone surveys were c
ompleted with 43% of participants; results support the effectiveness of the
prerelease intervention. Men who received the intervention were significan
tly more likely to use a condom the first time they had sex after release f
rom prison and also were less likely to have used drugs, injected drugs; or
shared needles in the first 2 weeks after release from prison. Implication
s for the development, implementation, and evaluation of prison-based HIV p
revention programs are discussed.