Dementia of the Alzheimer type among women

Citation
Jc. Nedoschill et al., Dementia of the Alzheimer type among women, F NEUR PSYC, 67(10), 1999, pp. 441-447
Citations number
50
Categorie Soggetti
Neurology
Journal title
FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE
ISSN journal
07204299 → ACNP
Volume
67
Issue
10
Year of publication
1999
Pages
441 - 447
Database
ISI
SICI code
0720-4299(199910)67:10<441:DOTATA>2.0.ZU;2-1
Abstract
Within the different kinds of dementia, Alzheimer's Disease (AD) obviously is the only one showing relevant gender differences, concerning epidemiolog y, risk factors and cognitive deficits. Women more often suffer from AD, ac hieve lower Mini Mental Status Test scores when demented and show lower ver bal skills. The possibility of using estrogen as a therapeutic agent, eithe r only or as an augmentation to acetylcholinesterase inhibitors, could beco me more important for clinical practice, as it is said to cause distinct im provements of cognitive skills. Epidemiological studies were able to show t hat estrogen replacement therapy in menopausal women lowers risk of AD.