The development of the autoperfusion balloon catheter provided the ability
to perform prolonged balloon inflations during angioplasty procedures. For
a number of years the autoperfusion balloon catheter was successfully used
to treat acute complications of percutaneous coronary interventions. Howeve
r, with the advent of stent implantation procedures and the use of platelet
glycoprotein Ilb/IIIa receptor inhibitors, the role of autoperfusion ballo
on angioplasty has decreased. However, the perfusion balloon may have an im
portant role in angioplasty and/or stenting of coronary lesions with unfavo
rable coronary anatomy and also in carotid angioplasty. The perfusion ballo
on also may be helpful for the treatment of in-stent restenosis. In the fut
ure the autoperfusion balloon or its principle may hold promise in emerging
interventions, such as gene therapy and vascular brachytherapy where prolo
nged interrupted of coronary circulation is required.