Determination of coupling constants by deconvolution of multiplets in NMR

The structures of multiplets in one- and two-dimensional NMR spectra can be simplified by recursive deconvolution in the frequency domain. Deconvoluti on procedures are described for in-phase and antiphase doublets of delta fu nctions. Recursive simplification is illustrated by applications to double- quantum-filtered correlation spectra (DQF-COSY) and selective correlation s pectra (soft-COSY). Coupling constants can be measured reliably even if sig nals of opposite signs lead to partial cancellation, (C) 1999 Academic Pres s.