Remarkable phosphodiester hydrolysis activity of a novel Ce-IV complex in neutral aqueous solutions

Authors
Baykal, U Akkaya, MS Akkaya, EU
Citation
U. Baykal et al., Remarkable phosphodiester hydrolysis activity of a novel Ce-IV complex in neutral aqueous solutions, J MOL CAT A, 145(1-2), 1999, pp. 309-312
Citations number
15
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
ISSN journal
13811169 → ACNP
Volume
145
Issue
1-2
Year of publication
1999
Pages
309 - 312
Database
ISI
SICI code
1381-1169(19990908)145:1-2<309:RPHAOA>2.0.ZU;2-Y
Abstract
A novel Ce-IV-complex of 1,4,7-tris(carbamoylmethyl)-1,4,7-triazacyclononan e has been synthesized. The complex is both stable in aqueous solutions at neutral pH and very efficient in promoting the hydrolysis of a phosphodiest er model compound and yeast tRNA(phe). The RNA model compound, 2-hydroxypro pyl-p-nitrophenylphosphate hydrolysis is accelerated 7400-fold at pH 7.5, a s a result of an unprecedented hydrolytic activity. (C) 1999 Elsevier Scien ce B.V. All rights reserved.