Antidepressant drugs that act on serotonin and noradrenergic systems may be
analgesic. The newer antidepressant mirtazapine (Remeron) has activity on
noradrenergic and serotonergic transmission and is approved for the treatme
nt of a Major Depressive Disorder. This paper describes a case that suggest
s that mirtazapine may also be useful in the treatment of chronic pain. J P
ain Symptom Manage 1999;18:382-385. (C) U.S. Cancer Pain Relief Committee,
1999.