Anaerobic calorimetry of the growth of Lactobacillus helveticus using a highly sensitive Bio-RCl

To meet the need for studies of anaerobic microbial and animal cell culture s involving much lower heat effects as compared to aerobic microbial cultur es, a bench scale calorimeter, Bio-RCl, has been improved for achieving a h igher long-term sensitivity. This newly improved Bio-RCl was used for heat measurement of anaerobic growth of Lactobacillus helveticus. The results sh owed that the bench-scale calorimetry has powerful potential for on-line mo nitoring and control of anaerobic bioprocesses as well as fundamental studi es, such as stoichiometry, thermodynamics and kinetics of cellular growth.