Transient DSC, a novel and rapid method for assessing pharmaceutical powder compacts

Authors
Ozao, R Ochiai, M Ichimura, Y Takahashi, H Takano, T
Citation
R. Ozao et al., Transient DSC, a novel and rapid method for assessing pharmaceutical powder compacts, J THERM ANA, 56(3), 1999, pp. 1311-1316
Citations number
9
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
ISSN journal
13886150 → ACNP
Volume
56
Issue
3
Year of publication
1999
Pages
1311 - 1316
Database
ISI
SICI code
1388-6150(1999)56:3<1311:TDANAR>2.0.ZU;2-5
Abstract
The previously described method involving the use of transient DSC was appl ied to pharmaceutical powder compacts and to ceramic powder compacts. The s amples were prepared by compressing powders of pentaerythritol tetraacetate and two kinds of alumina powder (differing in particle size distribution) up to a pressure of 20 MPa by using a jig. For pentaerythritol tetraacetate , a linear relationship was obtained between the parameter obtained by DSC and the compaction pressure.