The stability and thermal behaviour of chloramphenicol and various of its m
ixtures were investigated. The thermogravimetric and stability constant res
ults showed that the chloramphenicol base is thermally more stable than the
tablet in the studied formulation. The reduction in stability was attribut
ed to the presence of search in the formulation. The thermal decompositions
of the chloramphenicol base and the tablet obey first-order kinetics.