Complexation behaviour of polymers with pendant cyclodextrin side groups

The influence of the chain conformation on the formation of polymeric supra molecular complexes as well as the influence of the complexation on the con formation of the polymer chain has been studied. The complexation of pyrene into the cavity of beta-cyclodextrin (beta-CD) was investigated in aqueous solutions of beta-CD substituted poly(allylamine) (PAA) under variation of external parameters, i.e. temperature, pH, ionic strength and addition of urea. The observed changes of the complexation constant K for the formation of the 2:1 beta-CD/pyrene complex can be explained by a change of the chai n flexibility which leads to a variation of the mean distance between neigh bouring beta-CD-moieties along the polymer chain. The intra-chain associati on of the decyl group with beta-CD in PAA with co-pendant decyl and beta-CD is disrupted by the addition of 1-adamantanamine HCl resulting in a more e xtended structure of the polymer. The beta-CD moiety in PAA-CD shows one or der of magnitude greater affinity to 2-(p-toluidyl)naphthalene-6-sulfonate than the native beta-CD and the affinity increases further by the presence of decyl side groups.