Amantadine-induced peripheral neuropathy

Authors
Shulman, LM Minagar, A Sharma, K Weiner, WJ
Citation
Lm. Shulman et al., Amantadine-induced peripheral neuropathy, NEUROLOGY, 53(8), 1999, pp. 1862-1865
Citations number
6
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
53
Issue
8
Year of publication
1999
Pages
1862 - 1865
Database
ISI
SICI code
0028-3878(19991110)53:8<1862:APN>2.0.ZU;2-V
Abstract
We report a 48-year-old woman with a 17-year history of PD who developed a peripheral sensory-motor neuropathy secondary to chronic administration (8 years) of amantadine. Discontinuation of amantadine resulted in resolution of trophic skin ulcers, paresthesias, and distal weakness. Amantadine may b e hazardous to patients with severe and chronic livedo reticularis.