Insulin-like growth factors in low-turnover osteopathy and osteopenia

Although in the last decades great progress has been made concerning renal replacement therapy, renal osteodystrophy is still of major clinical import ance in patient; with chronic renal failure. Recently, there is a change in the spectrum of renal osteodystrophy in favor of low turnover lesions. Rec ent studies suggest that growth factors may be involved in the pathophysiol ogy of the different forms of renal osteodystrophy.