M. Charlson et al., Predictors and outcomes of cardiac complications following elective coronary bypass grafting, P ASS AM PH, 111(6), 1999, pp. 622-632
Citations number
65
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS
Our objective was to determine the predictors of cardiac complications amon
g a cohort of elective coronary artery bypass graft (CABG) surgery patients
and to determine the relationship of such complications to subsequent qual
ity of life and symptoms. A total of 248 patients were enrolled and 237 com
pleted 6 month follow-up. The combined rate of both major and minor cardiac
complications was 9.7% (n = 24). patients in this study were evaluated pre
operatively, monitored intraoperatively, followed immediately postoperative
ly and at 6 months. Major cardiac complications accounted for 3.6% (n = 9)
and minor complications for 6% (n = 15). Using multivariable logistic regre
ssion analysis, the predictors of major cardiac complications were receivin
g diuretics preoperatively (p = .01) and increased time during cross-clampi
ng (p = .006). At 6 months after surgery, 19% of the patients with postoper
ative cardiac complications experienced worsening of symptoms, in contrast
to only 8% of those without cardiac complications (p = .03). We concluded t
hat patients who were on preoperative diuretics and those who had longer cr
oss-clamp times were at higher risk of cardiac complications. The majority
of patients who had acute cardiac complications had improved function and s
ymptoms at 6 months postoperatively.