Early-onset periodontitis in a patient with Ehlers-Danlos syndrome type III

This case history describes the course of disease in a 17-year-old boy with Ehlers-Danlos syndrome type III and early-onset periodontitis. Flow cytome tric tests showed a reduced cell count in the specific immune system. Immun oglobulin concentrations in saliva and serum were within normal limits. Inf ection with T-lymphotropic viruses was excluded. The phagocytic capacity of the peripheral blood polymorphonuclear leukocytes was unimpaired. The anae robic infection present in the early-onset periodontitis was treated with s ystemic antibiotic therapy and closed curettage. Following 14 days of this treatment signs of acute inflammation subsided, and 18 months after therapy ended, a slight gain in clinical attachment was found, and bone growth was visible via radiology. However; a continuing lack of adequate oral hygiene represents a risk to the success of therapy in the long term.