Rheumatoid arthritis and many other systemic rheumatic diseases remain illn
esses of unknown cause for which current therapy is often inadequate. This
leads patients to seek questionable remedies, prominent among which are die
tary manipulations. Is there a role for dietary modifications in the routin
e therapy far patients with rheumatic diseases? This article discusses the
relationships between diets, fasting, elemental nutrition, vitamins, minera
ls, and foods for rheumatic diseases. Known scientific-based evidence for t
he use, safety, and efficacy of diets and dietary-related practices subscri
bed by patients with rheumatic diseases are presented. Studies that link di
et with arthritis offer the possibility of identifying new therapeutic appr
oaches for selected patients and of developing new insights to disease path
ogenesis. Dietary therapy for arthritis, however, is still being investigat
ed.