We have constructed and operated versatile miniature pressure cells designe
d for the in situ characterization of materials under combined high pressur
e-temperature (P-T) conditions. This provides an opportunity conveniently t
o perform laboratory experiments to synthesize and characterize novel mater
ials that may be stable only under high P-T conditions. The synthesis proce
ss may then be scaled up to an industrial level provided that such phase st
abilization occurs under modest P-T conditions. The pressure anvils consist
of cubic-zirconia, sapphire or diamond to obtain maximum pressures of 10-3
0 GPa. I cite selected examples of materials and minerals that have been in
vestigated in our laboratory, where the properties of the crystalline high-
pressure phase are radically different from those at ambient pressure, for
example, cubanite (CuFe2S3) and troilite (FeS). I discuss the possibility o
f pressure-induced amorphization and emphasize the occurrence of this pheno
menon in mineral-related materials.