Cf. Lawrence et al., N-trityl-aziridinyl(diphenyl)methanol as an effective catalyst in the enantioselective addition of diethylzinc to aldehydes, SYNLETT, (10), 1999, pp. 1571-1572
High levels of enantioselectivity have been achieved in the diethylzinc add
ition to both aromatic and aliphatic aldehydes, employing N-trityl-aziridin
yl(diphenyl)methanol as the chiral catalyst. The R- and S-antipodes of the
catalyst can readily be prepared from D- acid L-serine, respectively.