2-(alk-1 '-ynyl)-4,6-dimethoxy-1,3,5-triazines via Pd-mediated alkynylation of 2-chloro-4,6-dimethoxy-1,3,5-triazine

Authors
Menicagli, R Samaritani, S Gori, S
Citation
R. Menicagli et al., 2-(alk-1 '-ynyl)-4,6-dimethoxy-1,3,5-triazines via Pd-mediated alkynylation of 2-chloro-4,6-dimethoxy-1,3,5-triazine, TETRAHEDR L, 40(48), 1999, pp. 8419-8422
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
48
Year of publication
1999
Pages
8419 - 8422
Database
ISI
SICI code
0040-4039(19991126)40:48<8419:2'VPA>2.0.ZU;2-N
Abstract
In the presence of a catalytic amount of (Ph3P)(4)Pd, 2-chloro-4,6-dimethox y-1,3,5-triazine reacts with alk-1-ynes to give the corresponding 2-(alk-1' -ynyl)-derivatives in satisfactory yields. Depending on the nature of the a lk-1-ynes, Pd(10%)/C can also be used to catalyze the cross-coupling. (C) 1 999 Elsevier Science Ltd. All rights reserved.