Clinical practice guidelines (CPGs) are systematically developed statements
to assist practitioner and patient decisions about appropriate health case
for specific clinical circumstances. The implications of this definition a
re that: the methodologic perspective and operations for systematic develop
ment must be specified, a strategy is needed to account for the patient's p
erspective in the CPG development process and the clinical decision, and a
mechanism is required to determine how appropriateness ought to be conceptu
alized and defined. Addressing these issues, we review models of CPG develo
pment, outline challenges to evidence-based approaches to CPG development,
address unique factors relevant to the development of guidelines for the su
rgical community, introduce an Ontario practice guidelines strategy that us
es complementary methods of CPG development, and summarize the feedback pro
vided by the surgical community regarding the practice guidelines produced
in Ontario's cancer system.