Comparison of gadomer-17 and Gd-DTPA in image quality of contrast-enhancedMR angiographies using flow phantom model

The purpose of this study was to compare the image quality of 3D-TOF MR ang iography (MRA) using Gadomer-17 with that using Gd-DTPA in a flow phantom m odel, and to present preliminary data about the proper dose concentration o f Gadomer-17. In the visual analysis of Vessel conspicuity, we compared the quality of pre- and post-contrast MIP images. For quantitative analysis, t he signal intensities were measured in the axial base 3D-TOF images, and th en the relative contrast enhancement was calculated. The results of our stu dies were that: 1. Maximal signal intensities were obtained at 1 mmol/L of Gadomer-17 and 4 mmol/L of Gd-DTPA. 2. Flow-related signal loss was decreas ed by Gd-DTPA proportional to the concentration, but Gadomer-17 did not sho w such a dose accumulative effect. In conclusion, after comparing the resul ts of Gd-DTPA, it was clear that improved MRA images and higher signal inte nsities of vessels were obtained when lower concentrations of Gadomer-17 we re used.