Sonohysterography in post menopausal breast cancer patients taking Tamoxifen

The assessment of the clinical value of sonohysterography (SHG), to detect endometrial abnormalities in asymptomatic post-menopausal patients on Tamox ifen therapy is the aim of the present study. Out of 500 patients, 126 (25% ), were recognized to have an endometrial thickness of more than 8 mm at tr ansvaginal sonography (TVS). Among the 100 patients who underwent to the pr ocedure, SHG allowed to identify 53 endometrial polyps, all confirmed at hy steroscopy and hystology and 26 suspected hyperplasias. In this latter grou p, 12 hyperplasias were confirmed and two endometrial cancers were found at hystology. We did not have any false negative. SHG showed to be safe, easy to perform and more accurate than TVS alone in identifying endometrial pat hologies.