Endometrial adenocarcinoma in APA. Two cases of endometrial adenocarcinomaarising from atypical polypoid adenomyoma

Atypical polypoid adenomyoma (APA) most frequently presents as an endometri al polyp in premenopausal women and is believed to follow a benign course. In hysterectomy specimens from postmenopausal Japanease women, the endometr ium contained an APA with an area of endometrial adenocarcinoma. Aconvincin g transition zone between the APA and the adenocarcinoma was seen in our ca ses, suggesting that APA may develop into endometrial adenocarcinoma in pos tmenopausal women.