V. Zanagnolo et al., Clinical behaviour of 208 stage II endometrial cancer cases, 7TH BIENNIAL MEETING OF THE INTERNATIONAL GYNECOLOGIC CANCER SOCIETY, 1999, pp. 171-175
Two hundred and eight women with stage II disease, who underwent surgery be
tween 1980 and 1995 in 5 different Ob/Gyn department, were retrospectively
reviewed. 135 (64%) underwent total abdominal hysterectomy and 73 (36%) rad
ical hysterectomy. 66/111 (59%) of stage IIA and 67/92 (73%) of stage IIB u
nderwent adjuvant radiation therapy. Actuarial survival rate for stage IIA
and IIB endometrial cancer patients was 86% and 74% at 5 years, 82% and 68%
at 10 years respectively. Survival rate by surgical procedure was 79% in t
he simple hysterectomy group and 94% in the radical hysterectomy one at 5 y
ears, 74% and 94% respectively at 10 years. The difference did show a trend
but it was not statistically significant (P=0.085). Overall survival rate
by adjuvant treatment did not show any statistically significant difference
between the observation and the adjuvant therapy group.