Randomized study comparing the effect on bone mass of Calcitriol or Alendronate with or without HRT in postmenopausal women with osteopenia or osteoporosis

Authors
Casas, PF Delgado, E Vieder, C Gil, AB Bellman, D Delfino, M Mirkin, A Martino, M Paciocco, M Lopez, C Saenz, G Sottano, J Vidal, DR
Citation
Pf. Casas et al., Randomized study comparing the effect on bone mass of Calcitriol or Alendronate with or without HRT in postmenopausal women with osteopenia or osteoporosis, 9TH INTERNATIONAL MENOPAUSE SOCIETY WORLD CONGRESS ON THE MENOPAUSE, 1999, pp. 91-94
Citations number
8
Categorie Soggetti
Current Book Contents
Journal title
9TH INTERNATIONAL MENOPAUSE SOCIETY WORLD CONGRESS ON THE MENOPAUSE → ACNP
Year of publication
1999
Pages
91 - 94
Database
ISI
SICI code
Abstract
112 ambulatory, osteopenic or osteoporotic postmenopausal women (according with WHO criteria's). were allocated in four arms to receive: Calcitriol (C T) 0.50ug/day or Alendronate (AL) 10mg/day alone (arm C & D) or in combinat ion with CC-HRT (combined continuous oral micronized estradiol 2mg + Medrox iprogesterone 5mg/day) (arm A & B) during 12 months. Treatments efficacy wa s evaluate by changes in bone mineral density (BMD) after 12 months. All tr eatments increased BMD after one year. CC-THR combined with CT or AL was be tter than CT or AL alone. AL alone offered 3.5% increase of BMD and it was more effective than CT alone.