The influence of tibolone upon serum leptin levels in postmenopausal women

This study was designed in order to estimate serum leptin levels in postmen opausal women, as well as the possible correlation between serum leptin con centrations and the age, the duration of postmenopausal period and the body mass index (BMI) of these women. Furthermore, the objective of the study w as to assess the influence of tibolone on serum leptin concentrations in po stmenopausal women. Our results indicate that BMI values strongly regulate serum leptin concentrations. Moreover, long-term tibolone administration do es not seem to have any effect on leptin secretion.