M. Us-krasovec et R. Golouh, Papillary thyroid carcinoma with exuberant nodular fasciitis-like stroma in a fine needle aspirate - A case report, ACT CYTOL, 43(6), 1999, pp. 1101-1104
Citations number
25
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
BACKGROUND: Papillary thyroid carcinoma (PTC) with exuberant nodular fascii
tis-like stroma (PTC-ES) is a new morphologic variant of conventional PTC.
It is characterized by extensive reactive stromal proliferation, which may
occupy 60-80% of the tumor.
CASE: A 42-year-old female developed a tender, left-sided thyroid mass. The
fine needle aspiration biopsy specimen contained, besides diagnostic epith
elial features of PTC, many cohesive tissue fragments of cellular stroma.
CONCLUSION: A correct cytopathologic diagnosis of PTC-ES can be established
if both epithelial and stromal components are present in needle aspirates.