Sb. Soofer et S. Tabbara, Intraductal papilloma of the salivary gland - A report of two cases with diagnosis by fine needle aspiration biopsy, ACT CYTOL, 43(6), 1999, pp. 1142-1146
Citations number
19
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
BACKGROUND: Intraductal papillomas are rare, benign tumors most commonly en
countered in minor salivary glands. They are cystic, solitary neoplasms tha
t arise from ductal epithelium and produce painless swellings.
CASES: Two cases arose in major salivary glands. The first case was a super
ficial, firm mass at the superior edge of the parotid, cytologically evocat
ive of an adnexal tumor. A firm, submandibular mass in the second case was
diagnosed as a papillary neoplasm. Fluid was aspirated from bath cases. Thr
ee-dimensional epithelial clusters, some with a papillary configuration and
histiocytes, were the main cellular components. The majority of cells show
ed oncocytic differentiation; however, benign-appearing ductal cells in hon
eycomb sheets were also present. The first case also had occasional cells s
uggestive of sebaceous differentiation. The excised lesions were unilocular
cystic papillary neoplasms consistent with intraductal papilloma; focal se
baceous differentiation was noted in the first case.
CONCLUSION: Awareness of the cytologic features of intraductal papilloma of
the salivary glands should prompt its inclusion in the differential diagno
sis of papillary lesions of the head and neck.