BACKGROUND: Cystic lesions of deep soft tissues are rare and usually are co
mposed of a mesenchymal tumor undergoing necrosis or regressive changes. Be
nign cysts arising de novo are even mauls rave and may show features of dif
ferent morphology, potentially leading to an inexact diagnosis.
CASE: A 68-year-old male presented with a deep, firm mass in the upper part
of the back from which a dense liquid was aspirated, with an inconclusive
diagnosis. A second fine needle aspiration was performed and the lesion was
surgically biopsied. Immunohistochemical studies were also inconclusive, w
hile ultrastructural studies suggested an origin in the synovia of the scap
ular bursa.
CONCLUSION: The cytologic picture was suspicious for malignancy due to the
presence of numerous pseudopapillary structures, reminding us of a secondar
y deposit from a renal or thyroid primary or mesenchymal neoplasm. However,
the bland nuclear aspect suggested the benignity of the lesion, and the el
ectron microscopic features confirmed the synovial origin.