Small acoustic neuromas: Monitoring the growth rate by MRI

Citation
Gc. Modugno et al., Small acoustic neuromas: Monitoring the growth rate by MRI, ACT NEUROCH, 141(10), 1999, pp. 1063-1067
Citations number
25
Categorie Soggetti
Neurology
Journal title
ACTA NEUROCHIRURGICA
ISSN journal
00016268 → ACNP
Volume
141
Issue
10
Year of publication
1999
Pages
1063 - 1067
Database
ISI
SICI code
0001-6268(1999)141:10<1063:SANMTG>2.0.ZU;2-7
Abstract
In a proportion of small acoustic neuroma patients, monitoring with magneti c resonance imaging shows no volumetric increase of tumour size over the ye ars. The object of the study was to identify some indications for the clini cal choice between immediate surgery (with the related risks) and watchful waiting. We performed a retrospective study of 47 non-surgically-treated patients af fected by acoustic neuroma and monitored by gadolinium-enhanced MRI between January 1990 and February 1999. Six clinical Variables (tumour size, sex, age, initial symptoms, ABR pattern and duration of the symptoms) were exami ned by univariate analysis. Chi-square test and variance analysis were perf ormed to evaluate the statistical significance. In 30/47 (63.8%) cases, no growth was observed during the entire period of follow-up. In the remaining 17/47 (36.2%) patients, a volumetric increase w as detected, most often within the first year of observation. The clinical factors examined did not significantly correlate with growth. Despite the relatively short period of observation, we believe that immedia te surgery does not need to be considered mandatory for small acoustic neur omas, even in young patients. However the irregular behaviour of the tumour underlines the importance of monitoring with MRI at least once a year.