Severe flecainide acetate poisoning: A case report.

Citation
P. Maury et al., Severe flecainide acetate poisoning: A case report., ARCH MAL C, 92(2), 1999, pp. 273-277
Citations number
10
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX
ISSN journal
00039683 → ACNP
Volume
92
Issue
2
Year of publication
1999
Pages
273 - 277
Database
ISI
SICI code
0003-9683(199902)92:2<273:SFAPAC>2.0.ZU;2-Z
Abstract
Poisoning with flecainide acetate is rare and associated with a high mortal ity. This usually occurs after massive ingestion but can also be observed d uring therapeutic overdose in patients with renal failure or with amiodaron e therapy. The prognostic depends on the haemodynamic and rhythmic effects of the over dose one sign of which is widening of the QRS complexes. Major sodium bicar bonate or lactate infusion is the generally prescribed treatment. The autho rs report one case of a patient with renal failure on amiodarone who surviv ed a severe flecainide acetate overdose.