Poisoning with flecainide acetate is rare and associated with a high mortal
ity. This usually occurs after massive ingestion but can also be observed d
uring therapeutic overdose in patients with renal failure or with amiodaron
e therapy.
The prognostic depends on the haemodynamic and rhythmic effects of the over
dose one sign of which is widening of the QRS complexes. Major sodium bicar
bonate or lactate infusion is the generally prescribed treatment. The autho
rs report one case of a patient with renal failure on amiodarone who surviv
ed a severe flecainide acetate overdose.