The influence of some variables in the in vitro synthesis of dextran by dex
transucrase from Leusconostoc mesenteroides NRRL B512F, as well as in the a
cidic hydrolysis of the dextran produced, were studied in order to maximize
the production of clinical dextran (dextran 70 and dextran 40). The experi
ments were conducted using a factorial design and surface response analysis
.