Pharmacogenomics

Authors
Citation
W. Sadee, Pharmacogenomics, BR MED J, 319(7220), 1999, pp. 1286-NIL_22
Citations number
16
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
BRITISH MEDICAL JOURNAL
ISSN journal
09598138 → ACNP
Volume
319
Issue
7220
Year of publication
1999
Pages
1286 - NIL_22
Database
ISI
SICI code
0959-8138(19991113)319:7220<1286:P>2.0.ZU;2-4
Abstract
We all differ in our response to drug treatment-occasionally with dramatic effects. The era of "one drug fits all patients" is about to give way to in dividualised therapy matching the patient's unique genetic make up with an optimally effective drug.(1) Pharmacogenetics and pharmacogenomics are the emerging disciplines that ale leading the way towards individualised medici ne.(2 3) Initially, researchers focused their attention on pharmacogenetics -variations In single candidate genes responsible for variable drug respons e. Subsequently, studies involving the entire human genome broadened the sl ope of investigation, giving rise to pharmacogenomics as one of the "hottes t" fields in biotechnology today.