Obesity correlates with gastroesophageal reflux

Citation
Bl. Fisher et al., Obesity correlates with gastroesophageal reflux, DIG DIS SCI, 44(11), 1999, pp. 2290-2294
Citations number
18
Categorie Soggetti
Gastroenerology and Hepatology","da verificare
Journal title
DIGESTIVE DISEASES AND SCIENCES
ISSN journal
01632116 → ACNP
Volume
44
Issue
11
Year of publication
1999
Pages
2290 - 2294
Database
ISI
SICI code
0163-2116(199911)44:11<2290:OCWGR>2.0.ZU;2-L
Abstract
Thirty morbidly obese patients presenting for bariatric surgery were evalua ted for symptomatic and objective evidence of gastroesophageal reflux. Sixt een patients had heartburn while 14 were asymptomatic. All underwent esopha geal function testing; manometry was performed in all patients, pH monitori ng in 28, Patients with esophageal pH < 4 for more than 5% of observed time weighed more than those with normal acid exposure, 165.2 vs 129.8 kg (P < 0.01), and had significantly higher body mass indices, 56.5 vs 48.3 kg/m(2) (P < 0.05). Similarly, morbidly obese patients with abnormal reflux scores weighed significantly more and had greater body mass indices than patients with normal scores (P < 0.05). Lower esophageal sphincter pressure was hig her in patients. with normal esophageal acid exposure than in those with ab normal findings, 15.5 vs 12.5 mm Hg (P < 0.05). This study demonstrates a c orrelation between both weight and body mass index with gastroesophageal re flux.