Thirty morbidly obese patients presenting for bariatric surgery were evalua
ted for symptomatic and objective evidence of gastroesophageal reflux. Sixt
een patients had heartburn while 14 were asymptomatic. All underwent esopha
geal function testing; manometry was performed in all patients, pH monitori
ng in 28, Patients with esophageal pH < 4 for more than 5% of observed time
weighed more than those with normal acid exposure, 165.2 vs 129.8 kg (P <
0.01), and had significantly higher body mass indices, 56.5 vs 48.3 kg/m(2)
(P < 0.05). Similarly, morbidly obese patients with abnormal reflux scores
weighed significantly more and had greater body mass indices than patients
with normal scores (P < 0.05). Lower esophageal sphincter pressure was hig
her in patients. with normal esophageal acid exposure than in those with ab
normal findings, 15.5 vs 12.5 mm Hg (P < 0.05). This study demonstrates a c
orrelation between both weight and body mass index with gastroesophageal re
flux.