A branchial osteogenetic neoplasm affecting a barbel Barbus barbus plebejus
(Valenciennes, 1829) is described. The osteoblasts' pleomorphism, the lack
of a well-developed and complete separation, the presence of eccentric, te
rminal proliferative edges infiltrating the lining tissues and the abundant
tumour matrix suggest a histopathological diagnosis of a 'productive osteo
blastic osteosarcoma'. The occurrence of eosinophilic granule cells (EGCs)
scattered among neoplastic tissue is discussed in relation to the neoplasti
c growth and the inflammatory reaction, with reference to recent discoverie
s in mammalian mast cell biology.