BETA-GLUCOSYL AND BETA-GALACTOSYL TRANSFER CATALYZED BY BETA-1,4-GALACTOSYLTRANSFERASE IN PREPARATION OF GLYCOSYLATED ALKALOIDS

Authors
KREN V AUGE C SEDMERA P HAVLICEK V
Citation
V. Kren et al., BETA-GLUCOSYL AND BETA-GALACTOSYL TRANSFER CATALYZED BY BETA-1,4-GALACTOSYLTRANSFERASE IN PREPARATION OF GLYCOSYLATED ALKALOIDS, Journal of the Chemical Society. Perkin transactions. I, (17), 1994, pp. 2481-2484
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
17
Year of publication
1994
Pages
2481 - 2484
Database
ISI
SICI code
0300-922X(1994):17<2481:BABTCB>2.0.ZU;2-T
Abstract
Bovine beta-1,4-galactosyltransferase mediates the transfer of galacto se from uridine 5'-diphospho-galactose and also transfer of glucose fr om uridine 5'-diphosphoglucose to elymoclavine 2-acet-amido-2-deoxy-be ta-D-glucopyranoside 2a, yielding the respective diglycosides 3 and 4. Both reactions were optimised on a semipreparative scale. The product s were characterised by NMR spectroscopy and mass spectrometry.