Preliminary study on HA coating percutaneously implanted in bone

A comparative investigation on the possibility of hydroxyapatite (HA) coati ng and pure Ti column to form biological sealing with skin tissue was compl eted in this study. HA coating and pure Ti column were percutaneously impla nted in the tibia of rabbits. Compared with titanium (Ti) implant, HA coati ng forms epithelial sealing with skin tissue at 6 weeks postoperatively, wh ile the Ti implant may loosen from the implanted site and be lost. The Ti c olumn loosing rate at this time was 50%. However, once the Ti implant becom es fixed with the bone tissue, it can form epithelial sealing with skin tis sue just like the HA coating, at 8 weeks postoperatively. At 8 weeks postop eratively, the epithelial sealing is not destroyed in spite of the fact tha t the HA coating is biodegraded. Our results show that the HA coating can b ecome fixed with the bone faster than the Ti, which is beneficial for epith elial sealing formation. The main role of HA coating for epithelial sealing is beneficial for sealing at the initial period after it is implanted.