This manuscript provides a description of the methodology used in the Seaso
nal Variation of Blood Cholesterol Levels (SEASON) study, with the intent o
f informing the scientific community of the available data sets and to invi
te a dialogue with scientists in complementary fields. The primary aim of t
he SEASON study is to describe and delineate the causes of seasonal variati
on of blood lipid levels in the general population. This research project i
s designed specifically to systematically collect and analyze a number of i
mportant variables necessary to study the role of seasonality in blood lipi
ds and relevant covariates.