Haa. Naby et al., A convenient one-pot synthesis of pyrimido[4,5-b]quinolines as 5-deaza non-classical antifolate inhibitors, J CHEM R-S, (11), 1999, pp. 678-679
A convenient one-pot synthesis of pyrimido[4,5-b] quinolines as non-classic
al 5-deaza antifolate inhibitors by the reaction of 6-amino-4-oxo-2-thioxot
etrahydropyrimidine 1 with aromatic aldehydes and dimedone is reported.