M. Takino et al., Analysis of anatoxin-a in freshwaters by automated on-line derivatization-liquid chromatography-electrospray mass spectrometry, J CHROMAT A, 862(2), 1999, pp. 191-197
Anatoxin-a is a toxin produced from cyanobacterial blooms in freshwaters. I
n order to determine trace anatoxin-a in freshwaters, an automated on-line
derivatization procedure with fluorenyl methylchloroformate using liquid ch
romatography-electrospray ionization mass spectrometry was developed. Anato
xin-a was extracted using solid-phase extraction with adequate recovery (75
.7 +/- 7.2%, n = 6) at 20 ng/l. The limits of quantification and detection
were calculated to be 15.2 ng/l and 2.1 ng/l, respectively, using selected
ion monitoring. (C) 1999 Elsevier Science B.V. All rights reserved.