We report two female subjects with therapy-resistant cutaneous lupus erythe
matosus (LE), one with subacute cutaneous and the other chronic discoid LE,
both treated with extracorporeal photochemotherapy (ECP). The responses af
ter six and eight cycles of ECP led to a prolonged remission of 18 and 11 m
onths, respectively. ECP seems to be a treatment option for patients not re
sponding to or showing unwanted side-effects during conventional standard t
herapy. (C) 1999 Elsevier Science B.V. All rights reserved.