Synthesis of a new poly(carboxybetaine) with peptide main chain

Authors
Nagaya, J Uzawa, H Minoura, N
Citation
J. Nagaya et al., Synthesis of a new poly(carboxybetaine) with peptide main chain, MACRO RAPID, 20(11), 1999, pp. 573-576
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
MACROMOLECULAR RAPID COMMUNICATIONS
ISSN journal
10221336 → ACNP
Volume
20
Issue
11
Year of publication
1999
Pages
573 - 576
Database
ISI
SICI code
1022-1336(199911)20:11<573:SOANPW>2.0.ZU;2-6
Abstract
A new poly(carboxybetaine) whose main chain is composed of peptide bonds wa s synthesized from poly(gamma-methyl L-glutamate). The side chains of poly( gamma-methyl L-glutamate) were exchanged to carboxybetaine structures by th ree reactions. Our new poly(carboxybetaine) has 84% carboxybetaine structur es in the side chains, as determined by H-1 NMR measurements. The presence of betaine structures in the side chains was confirmed by viscosity measure ments.