Scatter and veiling glare are predominant sources of error in videodensitom
etric iodine quantification. Standard beam stop techniques such as lead str
ips or an array of lead discs, placed before the patients, have previously
been used to measure scatter and veiling glare in digital radiographic imag
es. However, these techniques significantly increase patient x-ray exposure
. In order to overcome this limitation, a scatter measurement technique bas
ed on sampled primary intensity has been investigated. This technique uses
an array of apertures in a lead sheet to sample the primary x-ray intensity
. The scatter-glare intensity in these locations is calculated by subtracti
ng the sampled primary intensity from an open field image which contains bo
th primary and scatter-glare. The calculated scatter-glare values can be in
terpolated or combined with digital filtration to estimate the scatter-glar
e intensity on a pixel by pixel basis. The technique was evaluated using a
Lucite(TM) step phantom and an anthropomorphic chest phantom. The average r
ms percentage errors of scatter and veiling glare estimation using bi-cubic
interpolation and digital filtration techniques were 8.02% and 7.53%, resp
ectively. The average rms percentage errors of primary intensity estimation
using hi-cubic interpolation and digital filtration techniques were 10.01%
and 8.91%, respectively. The x-ray exposure-area product (EAP) from the ap
erture array was only 4.38% of the EAP from the open field. These results i
ndicate that the scatter-glare intensity can be accurately estimated with m
inimal x-ray exposure using sampled primary intensity. (C) 1999 American As
sociation of Physicists in Medicine. [S0094-2405(99)03811-0].