Citation
Py. Kwok et Zj. Gu, Single nucleotide polymorphism libraries: why and how are we building them?, MOL MED TOD, 5(12), 1999, pp. 538-543
Citations number
21
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
MOLECULAR MEDICINE TODAY
ISSN journal
13574310
→ ACNP
Volume
5
Issue
12
Year of publication
1999
Pages
538 - 543
Database
ISI
SICI code
1357-4310(199912)5:12<538:SNPLWA>2.0.ZU;2-J
Abstract
A great deal of time and money is currently being invested In the productio
n of large libraries of single nucleotide polymorphisms (SNPs) - variations
of one nucleotide between the DNA sequence of individuals. This review com
pares and contrasts the available sources of SNP data, and describes the ra
tionale behind the SNP mapping efforts, from the study of common diseases t
o unraveling an individual's response to medication.