SEQUENCE POLYMORPHISM AT THE TETRANUCLEOTIDE REPEAT OF THE HUMAN BETA-ACTIN RELATED PSEUDOGENE H-BETA-AC-PSI-2 (ACTBP2) LOCUS

Authors
ROLF B SCHURENKAMP M JUNGE A BRINKMANN B
Citation
B. Rolf et al., SEQUENCE POLYMORPHISM AT THE TETRANUCLEOTIDE REPEAT OF THE HUMAN BETA-ACTIN RELATED PSEUDOGENE H-BETA-AC-PSI-2 (ACTBP2) LOCUS, International journal of legal medicine, 110(2), 1997, pp. 69-72
Citations number
9
Categorie Soggetti
Pathology
Journal title
International journal of legal medicine → ACNP
ISSN journal
09379827
Volume
110
Issue
2
Year of publication
1997
Pages
69 - 72
Database
ISI
SICI code
0937-9827(1997)110:2<69:SPATTR>2.0.ZU;2-1
Abstract
The tetranucleotide repeat polymorphism in the human beta-actin relate d pseudogene H-beta-Ac-psi-2 (ACTBP2) locus has become a widely used s hort tandem repeat (STR) system in paternity testing and human identif ication. The discrimination index of this locus has been reported to b e as high as 99.65%. To study the overall variability of this locus, 2 22 alleles were sequenced in our laboratory. Here, we report the seque nces of the 102 different alleles observed, In addition to the length polymorphism, up to ten different sequence variants for single fragmen t lengths have been detected.