Horner-Emmons synthesis with minimal purification using ROMPGEL: A novel high-loading matrix for supported reagents

Authors
Barrett, AGM Cramp, SM Roberts, RS Zecri, FJ
Citation
Agm. Barrett et al., Horner-Emmons synthesis with minimal purification using ROMPGEL: A novel high-loading matrix for supported reagents, ORG LETT, 1(4), 1999, pp. 579-582
Citations number
42
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
4
Year of publication
1999
Pages
579 - 582
Database
ISI
SICI code
1523-7060(19990826)1:4<579:HSWMPU>2.0.ZU;2-M
Abstract
[GRAPHICS] The synthesis and use of two novel high-loading Horner-Emmons ring-opening metathesis polymers are described, alpha,beta-Unsaturated ethyl esters (E:Z > 99:1) and alpha,beta-unsaturated nitriles (E:Z > 70:30) are obtained in excellent yields and purities from aldehydes with minimal purification.