A new method for the generation and cyclization of iminyl radicals via theHudson reaction

A mild new synthetic procedure has been developed for in situ generation an d cyclization of iminyl radicals onto pendant alkenes, followed by function alization of the resulting carbon radical by one of a variety of trapping r eagents, The key process in the method involves production of the iminyl ra dical via treatment of an aldoxime or ketoxime with readily available 2,6-d imethylbenzenesulfinyl chloride at -50 degrees C to room temperature (Hudso n reaction).