The urea-hydrogen peroxide complex: Solid-state oxidative protocols for hydroxylated aldehydes and ketones (Dakin reaction), nitriles, sulfides, and nitrogen heterocycles

Authors
Varma, RS Naicker, KP
Citation
Rs. Varma et Kp. Naicker, The urea-hydrogen peroxide complex: Solid-state oxidative protocols for hydroxylated aldehydes and ketones (Dakin reaction), nitriles, sulfides, and nitrogen heterocycles, ORG LETT, 1(2), 1999, pp. 189-191
Citations number
46
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
2
Year of publication
1999
Pages
189 - 191
Database
ISI
SICI code
1523-7060(19990729)1:2<189:TUPCSO>2.0.ZU;2-K
Abstract
An efficient solid state oxidation of organic molecules is described using a stable, inexpensive, and easily handled reagent, the urea-hydrogen peroxi de adduct, The generality of the reaction has been demonstrated in oxidatio n of several molecules, namely hydroxylated aldehydes and ketones (to hydro xylated phenols), sulfides (to sulfoxides and sulfones), nitriles (to amide s), and nitrogen heterocycles (to N-oxides).