A novel chiral pentamine ligand for enantioselective alpha-alkylation of acyclic lithium amide enolates. Optimization of chiral ligands for asymmetric reactions using solid-phase organic synthesis

Authors
Matsuo, J Odashima, K Kobayashi, S
Citation
J. Matsuo et al., A novel chiral pentamine ligand for enantioselective alpha-alkylation of acyclic lithium amide enolates. Optimization of chiral ligands for asymmetric reactions using solid-phase organic synthesis, ORG LETT, 1(2), 1999, pp. 345-347
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
2
Year of publication
1999
Pages
345 - 347
Database
ISI
SICI code
1523-7060(19990729)1:2<345:ANCPLF>2.0.ZU;2-8
Abstract
[GRAPHICS] A novel pentamine ligand has been developed for enantioselective alpha-alky lation of simple acyclic lithium amide enolates. It has been demonstrated t hat solid phase organic synthesis provides a powerful and rapid method for finding efficient chiral ligands.