Dyslexia represents a disorder of linguistic systems in the brain, wit
h evidence pointing to a deficit in phonologic processing as the most
consistent finding in children and adults with dyslexia. Using functio
nal MR imaging, it has become possible to localize the component proce
sses used in word identification: orthography, phonology, and lexical-
semantic processing. Activation of the inferior frontal gyrus region d
uring performance of a rhyming task may provide a neural signature for
phonologic processing, the core cognitive component in reading and dy
slexia.